Prospects for new vaccines against tuberculosis.
نویسنده
چکیده
The spectacular failure of the existing bacille Calmette-Guérin (BCG) vaccine in recent tuberculosis-control trials has prompted a search for potential replacements. Imaginative approaches currently under development include the modulation of BCG by the production of auxotrophic mutants or cytokine-secreting recombinants, and the development of subunit vaccines based on the major proteins of Mycobacterium tuberculosis.
منابع مشابه
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ورودعنوان ژورنال:
- BioTechniques
دوره 33 5 شماره
صفحات -
تاریخ انتشار 1995